RNF5: INHIBITING ANTIVIRAL IMMUNITY AND SHAPING VIRUS LIFE CYCLE

RNF5: inhibiting antiviral immunity and shaping virus life cycle

RNF5 is an E3 ubiquitin ligase involved in various physiological processes such as protein localization and cancer progression.Recent studies have shown that RNF5 significantly inhibits antiviral innate immunity by promoting the ubiquitination and degradation of STING and MAVS, which are essential adaptor proteins, as well as their downstream signa

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Bluff Body Drag Control using Synthetic Jet

The Tie Clip paper presents the results of an experimental investigation wherein the bullet form drag force as a function of oscillating actuator frequency, various voltage and for different orifice/slot configuration are studied.In order to perform the experiment, an axisymmetric bullet shape model with ellipsoidal nose was used in wind tunnel.The

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Evaluation of antibacterial properties and shear bond strength of orthodontic composites containing silver nanoparticles, titanium dioxide nanoparticles and fluoride: An in vitro study

ABSTRACT Objective: The study aimed at determining the antibacterial properties of composites containing silver nanoparticles (Ag NPs) or Beanie titanium dioxide nanoparticles (TiO2 NPs), and a fluoride-releasing composite against Streptococcus mutans and Lactobacillus acidophilus, and to evaluate the effect on shear bond strength (SBS) of nanopart

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A new model mimicking persistent HBV e antigen-negative infection using covalently closed circular DNA in immunocompetent mice.

Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a major health problem.HBV e EYE SHADOW antigen (HBeAg)-negative strains have become prevalent.Previously, no animal model mimicked the clinical course of HBeAg-negative HBV infection.To establish an HBeAg-negative HBV infection model, the 3.2-kb full-length

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